Reading Flashcards
7 cards from real ABD practice questions. Tap to flip, then mark Knew It or Still Learning โ missed cards come back until you master them.
Read the first 7 Reading flashcards as text
A dark-skinned patient has an asymmetric pigmented lesion with border irregularity, color variegation, and a 8 mm diameter that recently changed. Which malignancy is most concerning?
Answer: Melanoma
The ABCDE features (asymmetry, border, color, diameter, evolution) strongly suggest melanoma.
Which histologic parameter is the most important prognostic factor in cutaneous melanoma?
Answer: Breslow thickness
Breslow depth (tumor thickness in mm) is the strongest predictor of melanoma prognosis and staging.
A pearly papule with rolled borders and central telangiectasias on the nose is most likely:
Answer: Basal cell carcinoma
A pearly, telangiectatic papule with rolled borders is the classic presentation of basal cell carcinoma.
Which targeted therapy is used for melanoma harboring a BRAF V600E mutation?
Answer: Vemurafenib
Vemurafenib is a BRAF inhibitor indicated for BRAF V600E-mutant metastatic melanoma.
Actinic keratoses are considered precursors to which malignancy?
Answer: Squamous cell carcinoma
Actinic keratoses are premalignant lesions that may progress to squamous cell carcinoma.
Which immune checkpoint inhibitor targeting PD-1 is used in advanced melanoma?
Answer: Nivolumab
Nivolumab is an anti-PD-1 monoclonal antibody used to treat advanced melanoma.
A rapidly growing, dome-shaped nodule with a central keratin plug that may regress spontaneously is:
Answer: Keratoacanthoma
Keratoacanthoma is a rapidly growing crateriform nodule considered a well-differentiated SCC variant.