Practice Test GeeksAmerican Board of Dermatology (ABD) Practice Test
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Dermatologic Pharmacology Flashcards

7 cards from real ABD practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

Read the first 7 Dermatologic Pharmacology flashcards as text

  1. Methotrexate for psoriasis requires monitoring for toxicity of which organ?

    Answer: Liver

    Methotrexate can cause cumulative hepatotoxicity and hepatic fibrosis requiring monitoring.

  2. Which biologic targets TNF-alpha and is used for moderate-to-severe psoriasis?

    Answer: Adalimumab

    Adalimumab is a TNF-alpha inhibitor approved for plaque psoriasis and psoriatic arthritis.

  3. Dupilumab, used for moderate-to-severe atopic dermatitis, blocks signaling of:

    Answer: IL-4 and IL-13

    Dupilumab inhibits IL-4 receptor alpha, blocking IL-4 and IL-13 Th2 signaling.

  4. Before starting TNF-alpha inhibitor therapy, patients must be screened for:

    Answer: Latent tuberculosis

    TNF inhibitors can reactivate latent tuberculosis, so screening is required first.

  5. Cyclosporine's principal dose-limiting toxicity in dermatology is:

    Answer: Nephrotoxicity and hypertension

    Cyclosporine, a calcineurin inhibitor, commonly causes renal impairment and hypertension.

  6. Which class of biologics targeting IL-17 is highly effective for plaque psoriasis?

    Answer: Secukinumab

    Secukinumab is an IL-17A inhibitor with strong efficacy in plaque psoriasis.

  7. Apremilast, an oral psoriasis agent, works by inhibiting:

    Answer: Phosphodiesterase-4

    Apremilast is a PDE-4 inhibitor that reduces inflammatory cytokine production.