Dermatologic Pharmacology Flashcards
7 cards from real ABD practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Dermatologic Pharmacology flashcards as text
Isotretinoin is contraindicated in pregnancy because it is:
Answer: A potent teratogen
Isotretinoin is a powerful teratogen requiring iPLEDGE contraception monitoring.
Which laboratory value should be monitored during oral isotretinoin therapy?
Answer: Serum triglycerides
Isotretinoin commonly elevates triglycerides and liver enzymes, requiring lipid monitoring.
The mainstay systemic drug for severe nodulocystic acne is:
Answer: Oral isotretinoin
Oral isotretinoin is the most effective therapy for severe recalcitrant nodulocystic acne.
Spironolactone benefits acne in women mainly through:
Answer: Anti-androgen activity
Spironolactone blocks androgen receptors, reducing sebum production in hormonal acne.
Which topical antibiotic is combined with benzoyl peroxide to reduce bacterial resistance in acne?
Answer: Clindamycin
Benzoyl peroxide is added to clindamycin to limit C. acnes resistance.
Benzoyl peroxide reduces acne primarily by:
Answer: Oxidizing and killing C. acnes
Benzoyl peroxide releases free oxygen radicals that are bactericidal to C. acnes.
A common early side effect of starting topical tretinoin is:
Answer: Irritation and peeling
Topical tretinoin causes retinoid dermatitis with erythema, dryness, and peeling initially.