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Dermatologic Pharmacology Flashcards

7 cards from real ABD practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

Read the first 7 Dermatologic Pharmacology flashcards as text
  1. Isotretinoin is contraindicated in pregnancy because it is:

    Answer: A potent teratogen

    Isotretinoin is a powerful teratogen requiring iPLEDGE contraception monitoring.

  2. Which laboratory value should be monitored during oral isotretinoin therapy?

    Answer: Serum triglycerides

    Isotretinoin commonly elevates triglycerides and liver enzymes, requiring lipid monitoring.

  3. The mainstay systemic drug for severe nodulocystic acne is:

    Answer: Oral isotretinoin

    Oral isotretinoin is the most effective therapy for severe recalcitrant nodulocystic acne.

  4. Spironolactone benefits acne in women mainly through:

    Answer: Anti-androgen activity

    Spironolactone blocks androgen receptors, reducing sebum production in hormonal acne.

  5. Which topical antibiotic is combined with benzoyl peroxide to reduce bacterial resistance in acne?

    Answer: Clindamycin

    Benzoyl peroxide is added to clindamycin to limit C. acnes resistance.

  6. Benzoyl peroxide reduces acne primarily by:

    Answer: Oxidizing and killing C. acnes

    Benzoyl peroxide releases free oxygen radicals that are bactericidal to C. acnes.

  7. A common early side effect of starting topical tretinoin is:

    Answer: Irritation and peeling

    Topical tretinoin causes retinoid dermatitis with erythema, dryness, and peeling initially.