Ambulatory Care Test Ambulatory Care Ambulatory Care Pharmacology 3

Question 1

A 65-year-old patient with atrial fibrillation and a CrCl of 30 mL/min needs anticoagulation. Which direct oral anticoagulant requires the most significant dose adjustment?

Accepted Answer

Dabigatran

Answer

Dabigatran is predominantly renally cleared (80%) and is generally avoided in severe renal impairment.

Question 2

Which medication used for smoking cessation carries an FDA black box warning for neuropsychiatric events?

Accepted Answer

Varenicline

Answer

Varenicline (Chantix) carried a black box warning for serious neuropsychiatric events including depression, suicidal ideation, and behavior changes.

Question 3

A patient with gout is prescribed allopurinol. What is the recommended goal for serum uric acid to prevent recurrent attacks?

Accepted Answer

Less than 6 mg/dL

Answer

ACR guidelines recommend a serum uric acid target of less than 6 mg/dL for most gout patients on urate-lowering therapy.

Question 4

Which fluoroquinolone is associated with the highest risk of QT interval prolongation?

Accepted Answer

Moxifloxacin

Answer

Moxifloxacin has the greatest QTc-prolonging effect among fluoroquinolones and is avoided with other QT-prolonging drugs.

Question 5

An ambulatory patient with hypothyroidism should take levothyroxine at which time to optimize absorption?

Accepted Answer

30-60 minutes before breakfast on an empty stomach

Answer

Levothyroxine absorption is maximized when taken 30-60 minutes before breakfast without food or other medications.

Ambulatory Care Test Practice Test

Ambulatory Care Test Practice Test

Ambulatory Care Test Ambulatory Care Ambulatory Care Pharmacology 3