Assistant Laboratory Animal Technician Regulations and Compliance 1 Flashcards
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Which federal agency is responsible for conducting unannounced inspections of registered research facilities to ensure compliance with the Animal Welfare Act?
Answer: USDA APHIS Animal Care
The USDA APHIS Animal Care program conducts unannounced inspections of AWA-registered facilities twice per year to verify compliance with AWA standards. OLAW oversees PHS Policy compliance but does not conduct physical inspections.
Under the PHS Policy, an Institutional Animal Care and Use Committee (IACUC) must include at minimum how many members, and which role is always required?
Answer: At least 5 members, including a veterinarian and a community member not affiliated with the institution
PHS Policy requires a minimum of 5 IACUC members: a chair, a veterinarian with program authority, a practicing scientist, a non-scientist, and one member not affiliated with the institution. This composition ensures both scientific expertise and community oversight.
The 'Three Rs' framework, which underpins modern laboratory animal welfare regulations, stands for which of the following?
Answer: Replacement, Reduction, and Refinement
The Three Rs—Replacement (using non-animal alternatives when possible), Reduction (minimizing the number of animals used), and Refinement (improving procedures to minimize pain and distress)—are the foundational principles required by both the AWA and PHS Policy when designing animal studies.
Under the Animal Welfare Act, which of the following species is explicitly EXCLUDED from AWA protections?
Answer: Rats of the genus Rattus bred for use in research
The AWA explicitly excludes birds, rats of the genus Rattus, and mice of the genus Mus bred for use in research, as well as farm animals used in agricultural research. Guinea pigs, rabbits, and cats are all covered species under the AWA.
An institution's Animal Welfare Assurance with OLAW must be renewed or updated under which circumstance?
Answer: Whenever there is a significant change in the animal care and use program, such as a new Institutional Official
An institution must update its Animal Welfare Assurance with OLAW whenever there are significant programmatic changes, including a new Institutional Official (IO), changes in IACUC membership or structure, or major changes to facilities. OLAW must approve the updated Assurance before PHS-funded activities can continue.
Which document serves as the primary reference standard for AAALAC International accreditation and describes recommended practices for housing, husbandry, and veterinary care of laboratory animals?
Answer: The Guide for the Care and Use of Laboratory Animals
The Guide for the Care and Use of Laboratory Animals (published by the National Academies) is the primary standard used by AAALAC International when evaluating programs for accreditation. It provides performance-based standards covering animal environment, housing, management, and veterinary care.