ALAT ALAT Research Procedures and Techniques Questions and Answers 3

Question 1

Which needle gauge is most appropriate for intravenous injection in a mouse tail vein?

Accepted Answer

25–27 gauge

Answer

18 gauge

Answer

21 gauge

Answer

30 gauge

Question 2

What is the term for the dose of a substance given per unit of body weight in animal research?

Accepted Answer

mg/kg

Answer

Therapeutic index

Answer

Lethal dose

Answer

Dosing volume

Question 3

Before administering any experimental compound to a laboratory animal, the ALAT should verify:

Accepted Answer

That the compound has been approved by the IACUC protocol

Answer

That the compound was stored at room temperature

Answer

That no other animals in the room have received the compound

Answer

That the researcher has a PhD

Question 4

Which of the following is the correct site for subcutaneous injection in a mouse?

Accepted Answer

Scruff of the neck

Answer

Inner thigh

Answer

Base of the tail

Answer

Footpad

Question 5

What does 'PO' mean as a route of administration in laboratory animal research?

Accepted Answer

Per os (oral administration)

Answer

Intraperitoneal injection

Answer

Percutaneous ointment

Answer

Posterior ocular

Question 6

When restraining a rat for an injection, which method is correct?

Accepted Answer

Scruff the rat firmly behind the head while supporting its body weight

Answer

Grasp the rat by its tail only and hold it upside down

Answer

Place the rat in a mesh bag

Answer

Use heavy gloves only, without positional support