AKT Pharmacology and Prescribing 2

Question 1

A patient taking an SSRI for depression is prescribed tramadol for pain. What potentially life-threatening interaction should be monitored?

Accepted Answer

Serotonin syndrome

Answer

QT prolongation

Answer

Neuroleptic malignant syndrome

Answer

Malignant hyperthermia

Question 2

Which drug is absolutely contraindicated in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency due to risk of hemolytic anemia?

Accepted Answer

Primaquine

Answer

Amoxicillin

Answer

Metformin

Answer

Atenolol

Question 3

What is the primary mechanism of action of ACE inhibitors in treating hypertension?

Accepted Answer

Inhibiting the conversion of angiotensin I to angiotensin II

Answer

Blocking angiotensin II receptors directly

Answer

Increasing aldosterone secretion

Answer

Blocking calcium channels in vascular smooth muscle

Question 4

A patient with COPD requires antihypertensive therapy. If a beta-blocker is necessary, which agent is most appropriate?

Accepted Answer

Bisoprolol

Answer

Propranolol

Answer

Carvedilol

Answer

Nadolol

Question 5

Which antibiotic class exerts its bactericidal action by inhibiting bacterial cell wall peptidoglycan synthesis?

Accepted Answer

Beta-lactams

Answer

Fluoroquinolones

Answer

Macrolides

Answer

Aminoglycosides

Question 6

A patient starting methotrexate therapy for rheumatoid arthritis should receive concurrent supplementation with which vitamin?

Accepted Answer

Folic acid

Answer

Vitamin B12

Answer

Vitamin D

Answer

Vitamin C

Question 7

What is the current recommended first-line triple therapy regimen for H. pylori eradication in the United States?

Accepted Answer

Clarithromycin + amoxicillin + PPI

Answer

Amoxicillin + metronidazole + ranitidine

Answer

Tetracycline + bismuth + H2 blocker

Answer

Ciprofloxacin + metronidazole + PPI