AF AF Pharmacology & Medications

Question 1

Which class of anticoagulants is preferred over warfarin for non-valvular atrial fibrillation due to a more predictable pharmacokinetic profile?

Accepted Answer

Direct oral anticoagulants (DOACs)

Answer

DOACs such as apixaban, rivaroxaban, and dabigatran are preferred over warfarin for non-valvular AF due to predictable dosing, fewer drug interactions, and no routine INR monitoring.

Question 2

What is the primary goal of rate control therapy in atrial fibrillation?

Accepted Answer

Keep resting heart rate below 110 bpm

Answer

Rate control therapy aims to keep the resting ventricular rate below 110 bpm to reduce symptoms and prevent tachycardia-induced cardiomyopathy.

Question 3

Which beta-blocker is commonly used for rate control in AF patients with reduced ejection fraction?

Accepted Answer

Carvedilol

Answer

Carvedilol is a non-selective beta-blocker with alpha-blocking properties that provides rate control and has proven mortality benefit in heart failure with reduced ejection fraction.

Question 4

Amiodarone is classified as which Vaughan-Williams antiarrhythmic drug class?

Accepted Answer

Class III

Answer

Amiodarone is a Class III antiarrhythmic agent that primarily blocks potassium channels, prolonging the action potential duration and refractory period.

Question 5

What INR therapeutic range is targeted when using warfarin for stroke prevention in AF patients?

Accepted Answer

2.0–3.0

Answer

The target INR for warfarin in AF stroke prevention is 2.0–3.0, balancing stroke reduction against bleeding risk.

(AF) Atrial Fibrillation Certification Practice Test

(AF) Atrial Fibrillation Certification Practice Test

AF AF Pharmacology & Medications