Dental Pharmacology Flashcards
6 cards from real ADAT practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 6 Dental Pharmacology flashcards as text
Which local anesthetic has the longest duration of action and is most commonly used for prolonged dental procedures?
Answer: Bupivacaine
Bupivacaine has the longest duration of action among local anesthetics used in dentistry, making it ideal for lengthy procedures.
What is the maximum safe dose of lidocaine with epinephrine for a healthy adult patient?
Answer: 7.0 mg/kg up to 500 mg
The maximum safe dose of lidocaine with epinephrine is 7.0 mg/kg with an absolute maximum of 500 mg in healthy adults.
Which analgesic is contraindicated in patients with aspirin-exacerbated respiratory disease (AERD)?
Answer: NSAIDs
NSAIDs, including aspirin and ibuprofen, are contraindicated in AERD because they can trigger severe bronchospasm.
What is the mechanism of action of penicillin antibiotics?
Answer: Inhibit bacterial cell wall synthesis by binding PBPs
Penicillins bind penicillin-binding proteins (PBPs) and inhibit transpeptidation, disrupting bacterial cell wall synthesis.
Which drug interaction is most clinically significant when prescribing metronidazole to a dental patient?
Answer: Disulfiram-like reaction with alcohol
Metronidazole inhibits aldehyde dehydrogenase, causing a disulfiram-like reaction (flushing, nausea, vomiting) when combined with alcohol.
Which vasoconstrictors are most commonly combined with local anesthetics in dental cartridges in the US?
Answer: Epinephrine and levonordefrin
Epinephrine (1:50,000–1:200,000) and levonordefrin (1:20,000 with mepivacaine) are the two vasoconstrictors approved for use in US dental cartridges.