An 82-year-old woman with hypertension and diabetes presents with acute confusion, fever of 101.8°F, and suprapubic discomfort. Urinalysis shows pyuria and bacteriuria. Which is the most appropriate next step?
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A
Treat empirically with oral trimethoprim-sulfamethoxazole for 3 days
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B
Obtain urine culture and initiate empiric antibiotics appropriate for her age and comorbidities
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C
Obtain urine culture and defer antibiotics until culture results return
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D
Refer immediately to the ED for IV antibiotics