ABT Clinical Toxicology 2

Question 1

Which treatment is first-line for cyanide poisoning in the United States?

Accepted Answer

Hydroxocobalamin

Answer

Sodium thiosulfate alone

Answer

Methylene blue

Answer

Amyl nitrite alone

Question 2

Methylene blue is the antidote for which toxicological condition?

Accepted Answer

Methemoglobinemia

Answer

Carbon monoxide poisoning

Answer

Cyanide toxicity

Answer

Lead poisoning

Question 3

A urine drug screen using immunoassay is most prone to which analytical problem?

Accepted Answer

Cross-reactivity causing false positives

Answer

False negatives from dilution only

Answer

Inability to detect opioids

Answer

Degradation of all metabolites within 1 hour

Question 4

Which mechanism explains salicylate-induced hyperthermia in severe toxicity?

Accepted Answer

Uncoupling of oxidative phosphorylation

Answer

Inhibition of cyclooxygenase

Answer

Direct CNS fever center activation

Answer

Peripheral vasodilation only

Question 5

Which of the following is a contraindication to ipecac syrup administration in poisoned patients?

Accepted Answer

Caustic or corrosive substance ingestion

Answer

Aspirin ingestion within 30 minutes

Answer

Activated charcoal unavailability

Answer

Age over 12 years

Question 6

Carbon monoxide poisoning is treated with 100% oxygen primarily because it:

Accepted Answer

Competitively displaces CO from hemoglobin by mass action

Answer

Neutralizes CO in the bloodstream chemically

Answer

Stimulates erythropoiesis to replace damaged RBCs

Answer

Increases renal excretion of carboxyhemoglobin