ABPN American Board of Psychiatry and Neurology 3 — Questions and Answers
Question 1: Which vitamin deficiency causes Wernicke encephalopathy?
- Thiamine (B1) (Correct answer)
- Cobalamin (B12)
- Folate (B9)
- Niacin (B3)
Correct answer: Thiamine (B1)
Wernicke encephalopathy results from thiamine deficiency, often in chronic alcohol use.
Question 2: The triad of confusion, ophthalmoplegia, and ataxia defines:
- Wernicke encephalopathy (Correct answer)
- Korsakoff syndrome
- Delirium tremens
- Hepatic encephalopathy
Correct answer: Wernicke encephalopathy
Wernicke encephalopathy classically presents with confusion, ophthalmoplegia, and ataxia.
Question 3: Which mood stabilizer requires monitoring of serum levels, renal, and thyroid function?
- Lithium (Correct answer)
- Lamotrigine
- Bupropion
- Sertraline
Correct answer: Lithium
Lithium has a narrow therapeutic index and affects thyroid and renal function.
Question 4: Guillain-Barré syndrome typically presents with:
- Ascending symmetric weakness with areflexia (Correct answer)
- Descending weakness with hyperreflexia
- Unilateral facial droop
- Resting tremor
Correct answer: Ascending symmetric weakness with areflexia
GBS causes ascending flaccid paralysis with loss of deep tendon reflexes.
Question 5: Which diagnosis requires symptoms lasting at least 6 months in DSM-5 criteria?
- Schizophrenia (Correct answer)
- Brief psychotic disorder
- Schizophreniform disorder
- Major depressive episode
Correct answer: Schizophrenia
Schizophrenia requires continuous signs for at least 6 months.
Question 6: A cherry-red spot on the macula is associated with which condition?
- Tay-Sachs disease (Correct answer)
- Multiple sclerosis
- Huntington disease
- Myasthenia gravis
Correct answer: Tay-Sachs disease
Tay-Sachs disease features a macular cherry-red spot from GM2 ganglioside accumulation.
Question 7: Which antidepressant is contraindicated with tyramine-rich foods?
- MAO inhibitors (Correct answer)
- SSRIs
- Tricyclics
- SNRIs
Correct answer: MAO inhibitors
MAOIs plus tyramine can precipitate a hypertensive crisis.
ABPN American Board of Psychiatry and Neurology 3
Which vitamin deficiency causes Wernicke encephalopathy?