ABP Regenerative Techniques 4

Question 1

In the 'wound healing' model of periodontal regeneration, which event must occur FIRST for successful regeneration?

Accepted Answer

Vascular ingrowth into the clot

Answer

Vascular ingrowth into the fibrin clot is the first critical event in wound healing, providing oxygen and nutrients necessary for subsequent cell migration and proliferation.

Question 2

Platelet-rich fibrin (PRF) differs from PRP primarily because PRF:

Accepted Answer

Does not require addition of thrombin or calcium chloride to activate

Answer

PRF is a second-generation platelet concentrate that polymerizes naturally without the addition of exogenous thrombin or calcium chloride, forming a fibrin matrix through the body's own coagulation cascade.

Question 3

A 45-year-old patient presents with a 9mm probing depth and 6mm radiographic bone loss at the mesial of #19. Radiographically, the defect appears as a narrow angular defect. Which treatment would MOST likely yield the best regenerative outcome?

Accepted Answer

GTR with a barrier membrane ± bone graft

Answer

Deep, narrow intrabony defects with angular morphology respond best to GTR with or without bone graft, as these defects have favorable geometry for space maintenance and cell repopulation.

Question 4

Which term describes the property of a graft material that actively induces new bone formation by stimulating host cells to differentiate into osteoblasts?

Accepted Answer

Osteoinductive

Answer

Osteoinduction refers to the ability of a material to stimulate host mesenchymal cells to differentiate into bone-forming cells (osteoblasts), typically through growth factors like BMPs.

Question 5

The 'biological width' concept is relevant to regenerative therapy because violation of it can lead to:

Accepted Answer

Chronic osseous defect and bone loss around the restoration margin

Answer

Violation of biological width by restorative margins triggers a chronic inflammatory response that results in bone resorption as the periodontium attempts to re-establish the 2mm of supracrestal attachment.

(ABP) American Board of Periodontology Practice Test

(ABP) American Board of Periodontology Practice Test

ABP Regenerative Techniques 4