ABP Regenerative Techniques 3

Question 1

Xenografts used in periodontal bone regeneration are derived from which source?

Accepted Answer

Bovine or porcine bone

Answer

Xenografts are derived from non-human animal sources, most commonly bovine (cow) or porcine (pig) bone, which is processed to remove organic components and reduce antigenicity.

Question 2

A patient undergoes GTR for a 7mm three-wall intrabony defect. Six months post-op, re-entry shows 4mm of bone fill. What percentage of the defect was regenerated?

Accepted Answer

57%

Answer

4mm of bone fill in a 7mm defect equals 4/7 = 57% defect resolution, which is a standard way to express regenerative outcomes at re-entry.

Question 3

Which antibiotic is most commonly recommended as a systemic adjunct during regenerative periodontal surgery due to its anti-collagenase properties?

Accepted Answer

Doxycycline

Answer

Doxycycline is recommended as a systemic adjunct because it inhibits host-derived matrix metalloproteinases (MMPs) in addition to its antimicrobial properties, protecting the regenerating matrix.

Question 4

The Lindhe classification of furcation defects designates Class III as:

Accepted Answer

Through-and-through furcation involvement

Answer

Lindhe Class III furcation involvement means the furcation probe passes completely through the furcation from buccal to lingual (or mesial to distal), indicating a through-and-through defect.

Question 5

Which statement BEST describes the mechanism of action of recombinant human bone morphogenetic protein-2 (rhBMP-2) in periodontal regeneration?

Accepted Answer

It induces mesenchymal stem cell differentiation toward an osteoblastic lineage

Answer

rhBMP-2 is an osteoinductive growth factor that binds to cell surface receptors and induces uncommitted mesenchymal stem cells to differentiate into osteoblasts via the SMAD signaling pathway.

(ABP) American Board of Periodontology Practice Test

(ABP) American Board of Periodontology Practice Test

ABP Regenerative Techniques 3