ABP Regenerative Techniques 2

Question 1

Which growth factor found in platelet-rich plasma (PRP) is primarily responsible for stimulating angiogenesis during periodontal regeneration?

Accepted Answer

VEGF

Answer

VEGF (vascular endothelial growth factor) is the primary angiogenic growth factor in PRP that promotes new blood vessel formation essential for tissue regeneration.

Question 2

When using enamel matrix derivative (EMD) in periodontal regeneration, the protein primarily responsible for its regenerative effect is:

Accepted Answer

Amelogenin

Answer

Amelogenin constitutes approximately 90% of EMD proteins and is considered the primary active component responsible for cementum formation and periodontal regeneration.

Question 3

A critical factor distinguishing a space-maintaining membrane from one that does not require space maintenance in GTR is:

Accepted Answer

Membrane rigidity or stiffness

Answer

Membrane rigidity or stiffness is the critical property that allows a membrane to resist soft tissue collapse and maintain space for regeneration without requiring additional support.

Question 4

In the biology of periodontal regeneration, which cell type from the periodontal ligament is considered the most important progenitor for new cementum formation?

Accepted Answer

PDL fibroblasts near the cementum surface

Answer

PDL fibroblasts adjacent to the cementum surface are the key progenitor cells that differentiate into cementoblasts and produce new cementum during regeneration.

Question 5

Which type of bone defect has the WORST prognosis for regenerative therapy?

Accepted Answer

One-wall intrabony defect

Answer

One-wall intrabony defects provide the least osseous support and blood supply for regeneration, resulting in the poorest regenerative outcomes compared to multi-wall defects.

(ABP) American Board of Periodontology Practice Test

(ABP) American Board of Periodontology Practice Test

ABP Regenerative Techniques 2