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Regenerative Techniques Flashcards

7 cards from real ABP practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

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  1. Xenografts used in periodontal bone regeneration are derived from which source?

    Answer: Bovine or porcine bone

    Xenografts are derived from non-human animal sources, most commonly bovine (cow) or porcine (pig) bone, which is processed to remove organic components and reduce antigenicity.

  2. A patient undergoes GTR for a 7mm three-wall intrabony defect. Six months post-op, re-entry shows 4mm of bone fill. What percentage of the defect was regenerated?

    Answer: 57%

    4mm of bone fill in a 7mm defect equals 4/7 = 57% defect resolution, which is a standard way to express regenerative outcomes at re-entry.

  3. Which antibiotic is most commonly recommended as a systemic adjunct during regenerative periodontal surgery due to its anti-collagenase properties?

    Answer: Doxycycline

    Doxycycline is recommended as a systemic adjunct because it inhibits host-derived matrix metalloproteinases (MMPs) in addition to its antimicrobial properties, protecting the regenerating matrix.

  4. The Lindhe classification of furcation defects designates Class III as:

    Answer: Through-and-through furcation involvement

    Lindhe Class III furcation involvement means the furcation probe passes completely through the furcation from buccal to lingual (or mesial to distal), indicating a through-and-through defect.

  5. Which statement BEST describes the mechanism of action of recombinant human bone morphogenetic protein-2 (rhBMP-2) in periodontal regeneration?

    Answer: It induces mesenchymal stem cell differentiation toward an osteoblastic lineage

    rhBMP-2 is an osteoinductive growth factor that binds to cell surface receptors and induces uncommitted mesenchymal stem cells to differentiate into osteoblasts via the SMAD signaling pathway.

  6. During root surface conditioning prior to placement of EMD, the recommended concentration and type of acid used is:

    Answer: 24% EDTA gel for 2 minutes

    The manufacturer (Straumann/Biora) recommends PrefGel, which contains 24% EDTA, applied for 2 minutes to remove the smear layer and condition dentin before EMD application.

  7. Which of the following is the PRIMARY advantage of using a resorbable membrane over a non-resorbable membrane for GTR?

    Answer: Elimination of a second surgical procedure for membrane removal

    The primary advantage of resorbable membranes is that they eliminate the need for a second surgical procedure to remove the membrane, reducing patient morbidity and simplifying treatment.