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Glaucoma Flashcards

7 cards from real ABO practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

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  1. The LiGHT trial compared which two initial treatments for newly diagnosed open-angle glaucoma and ocular hypertension?

    Answer: Selective laser trabeculoplasty versus topical medications

    LiGHT showed first-line SLT was cost-effective and achieved drop-free control in most eyes with comparable quality of life.

  2. In the Ocular Hypertension Treatment Study, which baseline factor was identified as a strong independent predictor of conversion to glaucoma?

    Answer: Thin central corneal thickness

    Thinner central corneas were associated with significantly higher risk of developing POAG in OHTS.

  3. According to the Early Manifest Glaucoma Trial, each 1 mmHg of IOP reduction from baseline reduced the risk of progression by approximately:

    Answer: 10%

    EMGT found roughly a 10% reduction in progression risk for each mmHg of IOP lowering.

  4. Mitomycin C is used during trabeculectomy primarily to inhibit fibroblast proliferation. Which late complication is most associated with its use?

    Answer: Thin avascular cystic bleb with leak and endophthalmitis risk

    Antimetabolite-associated thin, ischemic blebs are prone to leaks, hypotony, blebitis, and bleb-related endophthalmitis.

  5. A 6-month-old presents with tearing, photophobia, corneal enlargement, and horizontal Descemet membrane breaks. What is the first-line treatment?

    Answer: Angle surgery such as goniotomy or trabeculotomy

    Primary congenital glaucoma is managed surgically with angle surgery; medications serve only as temporizing therapy.

  6. A glaucoma patient has a dense superior paracentral defect near fixation on a 24-2 field. Which test best characterizes and monitors this defect?

    Answer: Humphrey 10-2

    The 10-2 strategy tests the central 10 degrees with 2-degree spacing, giving far better resolution of paracentral damage.

  7. A child with a facial port-wine stain in the V1 distribution has elevated IOP and blood in Schlemm canal on gonioscopy. What is the main mechanism of glaucoma?

    Answer: Elevated episcleral venous pressure

    In Sturge-Weber syndrome, episcleral hemangiomas raise episcleral venous pressure, often combined with angle anomalies.