Cornea and External Disease Flashcards
7 cards from real ABO practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Cornea and External Disease flashcards as text
In the Herpetic Eye Disease Study, what did oral acyclovir 400 mg twice daily for 12 months do in patients with prior ocular HSV?
Answer: It lowered the rate of any ocular HSV recurrence by about half
HEDS showed that prophylactic oral acyclovir cut the recurrence of ocular HSV by about 45%, with the greatest benefit in patients with prior stromal keratitis.
Vesicles on the tip of the nose in herpes zoster ophthalmicus (Hutchinson sign) indicate involvement of which nerve?
Answer: Nasociliary nerve
The nasociliary nerve supplies the nasal tip and the globe, so involvement predicts a higher risk of ocular disease.
According to the Mycotic Ulcer Treatment Trial I, which topical agent gave better outcomes for filamentous fungal keratitis, especially Fusarium?
Answer: Natamycin
MUTT I found that natamycin gave better visual acuity and fewer perforations than voriconazole, with the largest difference for Fusarium.
What was the primary finding of the Steroids for Corneal Ulcers Trial (SCUT) for bacterial keratitis?
Answer: Adjunctive topical steroids did not significantly change 3-month best-corrected visual acuity overall
SCUT found no significant overall difference in 3-month BSCVA with adjunctive topical prednisolone, and no rise in adverse events.
A patient recovering from epidemic keratoconjunctivitis develops blurred vision from multiple central subepithelial infiltrates. Which adenovirus serotypes most typically cause this condition?
Answer: Types 8, 19, and 37
Adenovirus types 8, 19, and 37 cause epidemic keratoconjunctivitis and the immune subepithelial infiltrates that follow it.
Superior limbic keratoconjunctivitis is most strongly associated with which systemic condition?
Answer: Thyroid dysfunction
About 30% of patients with superior limbic keratoconjunctivitis have thyroid disease, so thyroid testing is recommended.
Which conjunctival biopsy finding supports a diagnosis of mucous membrane (ocular cicatricial) pemphigoid?
Answer: Linear deposition of immunoglobulin and complement along the epithelial basement membrane
Direct immunofluorescence that shows linear IgG, IgA, or C3 along the basement membrane zone is characteristic of mucous membrane pemphigoid.