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Core Knowledge and Fundamentals Flashcards

7 cards from real ABFM practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

Read the first 7 Core Knowledge and Fundamentals flashcards as text
  1. A 45-year-old man presents with fatigue and is found to have a fasting glucose of 118 mg/dL. How is this classified?

    Answer: Impaired fasting glucose (prediabetes)

    Impaired fasting glucose (prediabetes) is defined as fasting glucose 100–125 mg/dL; values ≥126 mg/dL on two occasions indicate diabetes.

  2. Which of the following is the most common cause of community-acquired pneumonia in otherwise healthy adults?

    Answer: Streptococcus pneumoniae

    Streptococcus pneumoniae remains the most common identifiable cause of community-acquired pneumonia across all age groups.

  3. A patient on metformin for type 2 diabetes is scheduled for a contrast CT scan. What is the recommended action regarding metformin?

    Answer: Discontinue metformin 48 hours before and restart 48 hours after if renal function is stable

    Metformin should be held 48 hours before and after iodinated contrast in patients at risk for contrast-induced nephropathy to prevent lactic acidosis.

  4. Which lipid abnormality pattern is most characteristic of metabolic syndrome?

    Answer: High triglycerides with low HDL

    Metabolic syndrome typically features hypertriglyceridemia and low HDL-cholesterol, along with abdominal obesity, hypertension, and impaired fasting glucose.

  5. A 70-year-old woman has a T-score of -2.7 on DXA. What does this indicate?

    Answer: Osteoporosis

    Osteoporosis is defined by a T-score of -2.5 or lower; this patient's score of -2.7 meets diagnostic criteria for osteoporosis.

  6. Which of the following best describes the mechanism of action of statins?

    Answer: Inhibit HMG-CoA reductase in hepatocytes

    Statins competitively inhibit HMG-CoA reductase, the rate-limiting enzyme in hepatic cholesterol synthesis, reducing LDL levels.

  7. Which preventive service has the strongest evidence for reducing cervical cancer mortality?

    Answer: HPV vaccination and cervical cytology/co-testing per guidelines

    HPV vaccination combined with Pap smear/co-testing per USPSTF/ACOG guidelines has the strongest evidence for reducing cervical cancer incidence and mortality.