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Core Knowledge and Fundamentals Flashcards

7 cards from real ABFM practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

Read the first 7 Core Knowledge and Fundamentals flashcards as text
  1. A 58-year-old man with hypertension and CKD stage 3 needs antihypertensive therapy. Which class is preferred as first-line in this setting?

    Answer: ACE inhibitor

    ACE inhibitors (or ARBs) are first-line in CKD with hypertension due to their nephroprotective effects by reducing intraglomerular pressure.

  2. According to the USPSTF, at what age should average-risk adults begin colorectal cancer screening?

    Answer: 45 years

    The USPSTF updated its recommendation in 2021 to begin colorectal cancer screening at age 45 for average-risk adults.

  3. Which finding on knee X-ray is most characteristic of osteoarthritis?

    Answer: Joint space narrowing with osteophytes

    Osteoarthritis classically shows joint space narrowing, subchondral sclerosis, subchondral cysts, and osteophyte formation on X-ray.

  4. A patient is started on warfarin for atrial fibrillation. Which INR range is the target for stroke prevention?

    Answer: 2.0–3.0

    The therapeutic INR range for atrial fibrillation anticoagulation is 2.0–3.0, balancing stroke prevention against bleeding risk.

  5. Which vaccine is recommended annually for all persons aged 6 months and older?

    Answer: Influenza vaccine

    The influenza vaccine is recommended annually for all persons ≥6 months of age due to antigenic drift of influenza strains each season.

  6. A 35-year-old woman is 8 weeks pregnant and screened for gestational diabetes. Which test is used at this early gestational age?

    Answer: Hemoglobin A1c

    Hemoglobin A1c or fasting plasma glucose is used in early pregnancy to screen for preexisting (overt) diabetes, not gestational diabetes.

  7. Which clinical feature best distinguishes bacterial tonsillitis from viral pharyngitis?

    Answer: Absence of cough with exudate, tender anterior cervical adenopathy

    The Centor/McIsaac criteria use absence of cough, tonsillar exudate, tender anterior cervical lymphadenopathy, and fever to predict streptococcal pharyngitis.