Practice Test Geeks(ABE) American Board of Endodontics Practice Test
← All ABE Flashcard Decks

Regenerative Endodontics Flashcards

7 cards from real ABE practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

Read the first 7 Regenerative Endodontics flashcards as text

  1. Platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) have been used as alternative scaffolds in REPs. Compared to blood clot alone, what primary advantage do these platelet concentrates offer?

    Answer: They contain a higher concentration of autologous growth factors (PDGF, TGF-β, VEGF)

    Platelet concentrates are enriched with growth factors (PDGF, TGF-β, VEGF, IGF) that may enhance stem cell recruitment, proliferation, and differentiation compared to a simple blood clot scaffold.

  2. Which of the following complications is MOST specifically associated with triple antibiotic paste use in regenerative endodontics?

    Answer: Crown discoloration due to minocycline

    Minocycline, a component of triple antibiotic paste, chelates calcium in dentin and causes intrinsic crown discoloration, which is the most clinically recognized complication of TAP use in anterior teeth.

  3. In regenerative endodontics, the histologic finding of cementum-like, bone-like, or periodontal ligament-like tissue rather than true pulp-dentin complex inside the canal is BEST explained by which concept?

    Answer: Ingrowth of multipotent cells from periapical tissues forming cementogenesis-type tissue

    Histologic studies of REP-treated teeth commonly show cementum, bone, and PDL-like tissue rather than true pulp-dentin complex, attributed to ingrowth of mesenchymal cells from periapical/PDL origin into the fibrin scaffold.

  4. According to current AAE position on REPs, which of the following patient factors is considered most critical when selecting between REP and apexification with MTA?

    Answer: Patient age and stage of root development (open vs nearly closed apex)

    Stage of root development (apex diameter, wall thickness, root length) and patient age are paramount — REPs are best suited for immature teeth where significant root development can still occur, offering the greatest benefit over apexification.

  5. Which irrigant sequence is recommended by the AAE for the first appointment of a regenerative endodontic procedure?

    Answer: NaOCl 1.5% → saline copious rinse → chlorhexidine 2%

    The AAE protocol recommends 1.5% NaOCl (to limit cytotoxicity to SCAP), followed by copious saline rinse, then 2% chlorhexidine for broad-spectrum disinfection at the first REP appointment.

  6. A 10-year-old presents with a necrotic immature mandibular second premolar and allergy to all antibiotics used in TAP/DAP. What is the MOST appropriate intracanal medicament for disinfection prior to REP scaffold induction?

    Answer: Calcium hydroxide paste

    Calcium hydroxide is an accepted alternative intracanal medicament for REPs when antibiotic pastes are contraindicated; it provides adequate disinfection with a favorable biocompatibility profile for apical stem cells.

  7. The concept of 'revascularization' in immature necrotic teeth refers to which biologic event?

    Answer: Ingrowth of new blood vessels and connective tissue into the canal space

    Revascularization describes the ingrowth of a new blood supply and connective tissue from the periapical region into the disinfected canal space, serving as the foundation for subsequent tissue maturation and root development.