ABD Inflammatory Dermatoses 4

Question 1

Atopic dermatitis in infancy classically involves which body regions?

Accepted Answer

Cheeks and extensor surfaces

Answer

Flexural creases only

Answer

Palms and soles

Answer

Scalp margins only

Question 2

A loss-of-function mutation in which gene is a major genetic risk factor for atopic dermatitis?

Accepted Answer

Filaggrin (FLG)

Answer

TP53

Answer

BRAF

Answer

PTCH1

Question 3

The 'atopic triad' associated with atopic dermatitis includes asthma, allergic rhinitis, and what?

Accepted Answer

Atopic dermatitis (eczema) itself

Answer

Psoriasis

Answer

Vitiligo

Answer

Urticaria pigmentosa

Question 4

Eczema herpeticum, a dermatologic emergency in atopic patients, is caused by disseminated infection with which virus?

Accepted Answer

Herpes simplex virus

Answer

Human papillomavirus

Answer

Coxsackievirus

Answer

Parvovirus B19

Question 5

Which topical calcineurin inhibitor is used as a steroid-sparing agent for atopic dermatitis, especially on the face?

Accepted Answer

Tacrolimus

Answer

Clobetasol

Answer

Calcipotriene

Answer

Salicylic acid

Question 6

Dupilumab, approved for moderate-to-severe atopic dermatitis, blocks the shared receptor subunit of which two cytokines?

Accepted Answer

IL-4 and IL-13

Answer

IL-17 and IL-23

Answer

TNF-alpha and IL-1

Answer

IL-5 and IL-6

Question 7

Dennie-Morgan folds and hyperlinear palms are physical clues supporting which diagnosis?

Accepted Answer

Atopic dermatitis

Answer

Bullous pemphigoid

Answer

Dermatitis herpetiformis

Answer

Pityriasis rosea