ABD Dermatologic Pharmacology 3

Question 1

Isotretinoin is contraindicated in pregnancy because it is:

Accepted Answer

A potent teratogen

Answer

Isotretinoin is a powerful teratogen requiring iPLEDGE contraception monitoring.

Question 2

Which laboratory value should be monitored during oral isotretinoin therapy?

Accepted Answer

Serum triglycerides

Answer

Isotretinoin commonly elevates triglycerides and liver enzymes, requiring lipid monitoring.

Question 3

The mainstay systemic drug for severe nodulocystic acne is:

Accepted Answer

Oral isotretinoin

Answer

Oral isotretinoin is the most effective therapy for severe recalcitrant nodulocystic acne.

Question 4

Spironolactone benefits acne in women mainly through:

Accepted Answer

Anti-androgen activity

Answer

Spironolactone blocks androgen receptors, reducing sebum production in hormonal acne.

Question 5

Which topical antibiotic is combined with benzoyl peroxide to reduce bacterial resistance in acne?

Accepted Answer

Clindamycin

Answer

Benzoyl peroxide is added to clindamycin to limit C. acnes resistance.

American Board of Dermatology (ABD) Practice Test