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Hematology & Coagulation Flashcards

7 cards from real AACC practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

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  1. What is the normal reference range for hemoglobin in adult males?

    Answer: 13.5–17.5 g/dL

    The normal hemoglobin range for adult males is 13.5–17.5 g/dL, reflecting their higher red cell mass compared to females.

  2. Which hematologic parameter directly measures the average volume of individual red blood cells?

    Answer: MCV

    Mean corpuscular volume (MCV) measures the average size of red blood cells in femtoliters (fL) and is used to classify anemias as microcytic, normocytic, or macrocytic.

  3. A patient's CBC reveals MCV of 70 fL, decreased serum ferritin, and elevated TIBC. Which condition is most consistent with these findings?

    Answer: Iron deficiency anemia

    Iron deficiency anemia presents with low MCV (microcytic), decreased ferritin (depleted iron stores), and elevated TIBC (increased iron-binding capacity due to low saturation).

  4. Which white blood cell type normally comprises the largest percentage of circulating leukocytes in a healthy adult?

    Answer: Neutrophils

    Neutrophils account for 50–70% of circulating white blood cells and serve as the primary defense against bacterial infections.

  5. What is the primary function of platelets in the hemostatic process?

    Answer: Forming the initial platelet plug at sites of vascular injury

    Platelets adhere to damaged subendothelial collagen, activate, and aggregate to form the primary platelet plug, initiating primary hemostasis.

  6. A reticulocyte count of 8% in a patient with hemolytic anemia indicates what about the bone marrow's response?

    Answer: Appropriate hyperproliferative response to red cell destruction

    An elevated reticulocyte count in hemolytic anemia reflects accelerated erythropoiesis as the bone marrow compensates for increased red cell destruction.

  7. Which of the following is the correct interpretation of a peripheral blood smear showing hypersegmented neutrophils and oval macrocytes?

    Answer: Megaloblastic anemia

    Hypersegmented neutrophils (>5 lobes) and oval macrocytes on peripheral smear are hallmark findings of megaloblastic anemia, caused by vitamin B12 or folate deficiency impairing DNA synthesis.