FREE KAPS Drug Formulation and Development Questions and Answers
Which excipient is commonly used to enhance the dissolution rate of poorly soluble drugs?
Hydrophilic excipients like polyvinylpyrrolidone (PVP) are often used to improve the dissolution of poorly soluble drugs by increasing their wettability.
What is the primary purpose of enteric coating on tablets?
Enteric coatings protect the drug from being released in the acidic environment of the stomach and ensure it is released in the intestines where the pH is higher.
Which formulation technique is commonly used for sustained-release drug delivery?
Matrix systems are a popular technique for sustained-release formulations, allowing the drug to be released slowly over time.
Why are nanoparticles increasingly used in drug delivery systems?
Nanoparticles enhance the bioavailability of drugs by improving solubility, targeting specific tissues, and enabling controlled release.
Which method is typically used to prepare liposomes for drug delivery?
The thin-film hydration method is widely used to prepare liposomes, ensuring proper encapsulation of the drug within the lipid bilayer.
What is the role of surfactants in pharmaceutical suspensions?
Surfactants reduce the surface tension between the drug particles and the liquid medium, improving dispersion and stability of the suspension.