PTCB Pharmacology #5

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What is the PH of the solution if the ratio of ionized to unionized drug species is 103 and PKa = 2.2?

Correct! Wrong!

The following formula can be used to determine the pH of a solution:
pH = log ionize/unionize + pKa
= log 103 + 2.2
= 2.2 + 3
= 5.2

Which drug classification does amlodipine belong to?

Correct! Wrong!

Explanation:
Calcium channel blocker amlodipine

How much atropine is needed to make 240cc so that 1 teaspoonful of the solution diluted to 1 pint yields a 1 in 500 solution?

Correct! Wrong!

To address a situation like this, we must first determine the amount of medication contained in the final solution.
1 pint of atropine contains 1 in 500 soln of atropine.
0.96 gm atropine = 480 x 1 /500
Because 0.96 grams of drug must be present in 1 teaspoonful of drug solution, we can conclude:
0.96 gram in 5cc (1 teaspoonful).
240cc solution requires
= 240 x 0.96/5 = 46.08 gm of atropine.

All of the following ADHD drugs are stimulants, with the exception of which one?

Correct! Wrong!

Explanation:
Stimulant drugs such as Vyvanse, Adderall, and Ritalin are used to treat ADHD.

All of the following drugs are used topically to treat acne vulgaris, with the exception of which one?

Correct! Wrong!

Explanation:
Acne vulgaris is treated with adapalene, salicylic acid, and benzoyl peroxide used topically.

Lotrel's generic name is which of the following medications?

Correct! Wrong!

Explanation:
Lotrel's generic name is amlodipine - benazepril.

What is the dose of a drug in cc for a 15-month-old infant if the dropper is calibrated to give 325 mg of iron sulfate in 0.6 cc and the adult dose of the drug is 325 mg?

Correct! Wrong!

0.06cc. Fried's rule is as follows:
12 months of age multiplied by 150 x adult dose
32.5 mg = 15 x 325/150
Because the dropper is calibrated to give 325 mg of Iron sulfate in 0.6 cc:
0.06cc = 0.6 x 32.5/325

A physician has prescribed 15 mL of Brand X antiacid Suspension to be taken every other day. How long will the bottle last?

Correct! Wrong!

The correct answer:
6 days

Which of the vitamins listed below is water soluble?

Correct! Wrong!

Explanation:
Vitamin C is a water-soluble nutrient.

All of the drugs listed below are used to treat angina, with the exception of which one?

Correct! Wrong!

Explanation:
Angina is treated with nitroglycerin, isosorbide mononitrate, and isosorbide dinitrate.

600 gm white petrolatum is required by a compounded prescription. How many 1 pound jars should you buy so that you have enough to make this recipe?

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The correct answer:
2 jars

Which of the following pharmaceutical kinds can be used to treat depression?

Correct! Wrong!

Explanation:
SSRIs can be used to treat depression.

Which of the following drugs has the generic name olanzapine?

Correct! Wrong!

Explanation:
Zyprexa's generic name is olanzapine.

What is the generic name for the erectile dysfunction medicine tadalafil?

Correct! Wrong!

Explanation:
Cialis is known by its generic name, tadalafil.

If you're on a monoamine oxidase inhibitor (MAOI), you should avoid foods and drinks that contain?

Correct! Wrong!

Explanation:
Patients taking a monoamine oxidase inhibitor (MAOI) should avoid tyramine-containing foods and beverages.

In individuals with a sulfa allergy, which of the following drugs should be avoided or taken with caution?

Correct! Wrong!

Explanation:
In people who have a sulfa allergy, hydrochlorothiazide should be avoided or used cautiously.

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