FREE Pharmacology Pharmacodynamics Questions and Answers
What is the primary function of a drug receptor in pharmacodynamics?
Drug receptors are typically proteins that interact with drugs, triggering a biological response. They are key players in determining the drug's efficacy and potency.
An agonist is a substance that:
An agonist binds to a receptor and mimics the action of endogenous substances, leading to a pharmacological effect.
Which of the following best describes the therapeutic index (TI) of a drug?
The therapeutic index (TI) is calculated as TD50 (toxic dose in 50% of the population) divided by ED50 (effective dose in 50% of the population). A higher TI indicates a safer drug.
Which term describes the maximum effect that a drug can produce, regardless of dose?
Efficacy is the ability of a drug to produce a maximum therapeutic effect. It is different from potency, which is the amount of drug needed to achieve a specific effect.
If a drug binds to a receptor but does not activate it and instead prevents other substances from binding, it is classified as:
An antagonist binds to a receptor without activating it and blocks agonists or other substances from binding, thereby preventing a biological response.
