Free LST Antigen Questions and Answers — Questions and Answers
Question 1: What is the primary function of lymphocytes in the immune system?
- Fight infections and provide immunity (Correct answer)
- Produce red blood cells
- Transport oxygen
- Regulate blood pressure
Correct answer: Fight infections and provide immunity
Lymphocytes are a type of white blood cell that plays a critical role in the immune response by fighting infections and providing immunity.
Question 2: What are the main types of lymphocytes involved in antigen recognition?
- T cells and B cells (Correct answer)
- Erythrocytes and leukocytes
- Platelets and monocytes
- Neutrophils and basophils
Correct answer: T cells and B cells
T cells and B cells are the primary lymphocytes involved in antigen recognition and immune response.
Question 3: What molecule on the surface of B cells is responsible for antigen recognition?
- B cell receptor (BCR) (Correct answer)
- T cell receptor (TCR)
- Major histocompatibility complex (MHC)
- Complement proteins
Correct answer: B cell receptor (BCR)
The B cell receptor (BCR) on the surface of B cells binds to specific antigens, initiating the immune response.
Question 4: What is the role of T cell receptors (TCRs) in antigen recognition?
- They bind to antigens presented by MHC molecules on antigen-presenting cells (Correct answer)
- They produce antibodies
- They phagocytize pathogens
- They release histamine
Correct answer: They bind to antigens presented by MHC molecules on antigen-presenting cells
T cell receptors (TCRs) on T cells recognize and bind to antigens presented by MHC molecules on the surface of antigen-presenting cells.
Question 5: Which type of MHC molecule presents endogenous antigens to CD8+ T cells?
- MHC class II
- MHC class I (Correct answer)
- MHC class III
- MHC class IV
Correct answer: MHC class I
MHC class I molecules present endogenous antigens (from within the cell) to CD8+ cytotoxic T cells.
Question 6: What type of antigens do MHC class II molecules present?
- Exogenous antigens (Correct answer)
- Self-antigens
- Endogenous antigens
- Viral antigens
Correct answer: Exogenous antigens
MHC class II molecules present exogenous antigens (from outside the cell) to CD4+ helper T cells.
Question 7: What is the initial event in the lymphocyte activation process?
- Recognition of an antigen by a specific receptor on the lymphocyte (Correct answer)
- Proliferation of lymphocytes
- Release of antibodies
- Migration to the site of infection
Correct answer: Recognition of an antigen by a specific receptor on the lymphocyte
The initial event in lymphocyte activation is the recognition of an antigen by a specific receptor on the lymphocyte.
Question 8: What is clonal expansion in the context of lymphocyte activation?
- Rapid proliferation of lymphocytes that have recognized a specific antigen (Correct answer)
- Differentiation into various cell types
- Secretion of cytokines
- Phagocytosis of pathogens
Correct answer: Rapid proliferation of lymphocytes that have recognized a specific antigen
Clonal expansion is the process by which lymphocytes that have recognized a specific antigen rapidly proliferate to mount an effective immune response.
Question 9: Which cells are considered professional antigen-presenting cells (APCs)?
- Dendritic cells, macrophages, and B cells (Correct answer)
- Red blood cells and platelets
- Neutrophils and eosinophils
- Basophils and mast cells
Correct answer: Dendritic cells, macrophages, and B cells
Dendritic cells, macrophages, and B cells are professional antigen-presenting cells that process and present antigens to T cells.
Question 10: What cytokine is essential for the proliferation of activated T cells?
- Interleukin-2 (IL-2) (Correct answer)
- Interleukin-1 (IL-1)
- Interleukin-4 (IL-4)
- Interferon-gamma (IFN-γ)
Correct answer: Interleukin-2 (IL-2)
Interleukin-2 (IL-2) is a cytokine that is crucial for the proliferation and survival of activated T cells.
Question 11: How do cytotoxic T cells kill infected cells?
- By secreting perforin and granzymes that induce apoptosis (Correct answer)
- By phagocytosis
- By releasing antibodies
- By producing histamine
Correct answer: By secreting perforin and granzymes that induce apoptosis
Cytotoxic T cells kill infected cells by secreting perforin and granzymes, which induce apoptosis in the target cells.
What is the primary function of lymphocytes in the immune system?