FREE ACRP Clinical Trial Monitoring Question and Answers
What are researchers required to get before volunteers can participate in the study?
Before volunteers can participate in a study, researchers are required to obtain informed consent from them. Informed consent involves providing detailed information about the study, including its purpose, procedures, potential risks and benefits, confidentiality measures, and the volunteer's right to withdraw at any time. Participants must fully understand this information and voluntarily agree to participate before they can join the study. This ensures that participants are aware of what is involved and can make an informed decision about their participation.
Why are case studies NOT always the best approach when doing clinical research?
Case studies are detailed examinations of specific individuals, groups, events, or phenomena. While they provide valuable insights into particular cases and can offer rich, detailed information, they have limitations in terms of generalizability. Since case studies focus on specific, often unique cases, the findings and conclusions drawn from them may not be applicable or representative of broader populations or situations. This lack of generalizability is a key drawback of using case studies as a research approach, particularly when the goal is to make broader conclusions that apply to a larger population.
The fact that individuals making higher incomes frequently have more years of schooling is an example of a/an _____.
This scenario demonstrates a correlation between two variables: income and years of schooling. A correlation implies that there is a statistical relationship or association between these variables—specifically, individuals with more years of schooling tend to earn higher incomes. However, it's important to note that correlation does not imply causation. In other words, while there is a relationship between these variables, having more years of schooling does not directly cause individuals to earn higher incomes; other factors could be influencing this relationship.
One of the last steps of a clinical trial is to monitor the participants:
In a clinical trial, one of the final steps is to monitor the participants over longer periods of time to assess the long-term effects, safety, and efficacy of the treatment or intervention being studied. This monitoring is crucial for evaluating the durability of the treatment and identifying any potential adverse effects that may emerge over time. Tracking participants over extended periods allows researchers to gather comprehensive data on the treatment's impact and safety profile.
Why do psychologists do clinical research?
Psychologists conduct clinical research to deepen their understanding of abnormal thoughts, feelings, and behaviors, aiming to uncover the underlying mechanisms of psychological disorders. Through research, psychologists identify effective and safe treatment approaches that can benefit individuals with mental health conditions. Getting published in peer-reviewed journals and interacting with diverse populations may also be outcomes of clinical research, but the primary goal is to advance knowledge and improve treatment outcomes in the field of psychology.
If your research design required a fair degree of control over the setting of the research conducted, which type of design should be utilized?
Lab research, also known as laboratory research, is the type of research design that provides a high degree of control over the setting and conditions of the study. In lab research, experiments are conducted in a controlled environment, often within a laboratory setting. This controlled setting allows researchers to manipulate variables and conditions precisely to study cause-and-effect relationships while minimizing external influences. Lab research is particularly useful when a researcher needs to control for confounding factors and isolate specific variables of interest.
When might experimenter bias be a worry?
Experimenter bias occurs when the researcher's expectations or preferences unconsciously influence the outcome of an experiment. This bias can be a concern when the results are subjective or when the experimenter has a vested interest in a particular outcome. It can lead to unintentional manipulation of the study conditions or the interpretation of results, potentially skewing the findings.
To mitigate experimenter bias, researchers employ various methods such as blinding, randomization, and rigorous adherence to scientific protocols. Blinding, in particular, involves keeping the experimenter unaware of which participants belong to which group (e.g., control or experimental), thereby reducing the influence of bias on the study outcomes.
Sometimes, researchers in a clinical trial compare the new treatment to:
In clinical trials, researchers often compare a new treatment or intervention to an established treatment that is already in use or considered the current standard of care for a specific condition. This comparison allows researchers to assess the effectiveness and safety of the new treatment relative to existing options. By comparing the new treatment to an established one, researchers can evaluate whether the new approach offers improvements in outcomes, fewer side effects, or other benefits compared to the current standard of care. This type of comparison is crucial for determining the value and potential impact of the new treatment being studied. Comparisons to water, aspirin, or the age of the participant are less relevant in this context.
What are the two possible settings for psychological research?
Psychological research can be conducted in two primary settings:
Lab Research: This involves controlled experiments conducted in a laboratory setting where researchers can manipulate variables and control conditions to study specific psychological phenomena under controlled and standardized conditions.
Field Research: This type of research takes place in real-world settings, such as natural environments or everyday contexts, where researchers observe behavior and gather data in naturalistic settings without manipulating variables as directly as in a lab.
Both settings offer distinct advantages and challenges, and researchers may choose between them based on their research questions, objectives, and practical considerations.
What is the difference between control and experimental groups in a research study?
In a research study, the control group and experimental group are used to compare the effects of a treatment or intervention. The control group serves as a baseline for comparison because it does not receive the experimental treatment or intervention being studied. This allows researchers to isolate the effects of the treatment by comparing outcomes between the group that receives the treatment (experimental group) and the group that does not (control group).
What is the difference between correlation and causation?
Correlation refers to a statistical relationship between two variables, meaning that as one variable changes, the other variable tends to change in a consistent way (positively, negatively, or not at all). However, correlation does not imply causation; it simply indicates that the variables are associated in some manner.
Causation, on the other hand, asserts that one variable directly causes a change in another variable. Establishing causation requires more rigorous evidence, often involving controlled experiments and the demonstration of a direct cause-and-effect relationship between variables.